Oral supplemental interventions for the 6 management of recurrent aphthous stomatitis (ras) – A systematic review and meta-analysis

Abstract

Recurrent aphthous stomatitis (RAS) is described as a painful, recurrent oral mucosal ulcerative condition in otherwise healthy individuals. Treatment objectives include pain relief/reduction, prevention of secondary infection, promoting healing and reducing recurrence. Conventional treatment modalities include topical or systemic corticosteroids, analgesics and antiseptic mouth rinses. Recent evidence suggests a therapeutic role for oral supplementation in the management of RAS.