dc.contributor.advisor | Bendou, Hocine | |
dc.contributor.author | Mfuphi, Nomlindelo Witness | |
dc.date.accessioned | 2022-10-28T12:59:15Z | |
dc.date.available | 2022-10-28T12:59:15Z | |
dc.date.issued | 2022 | |
dc.identifier.uri | http://hdl.handle.net/11394/9394 | |
dc.description | >Magister Scientiae - MSc | en_US |
dc.description.abstract | Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous malignancy
that is driven by complex gene regulatory networks (GRNs). Numerous genes exert
distinct effects on the progression and therapeutic outcome of DLBCL. Previous studies
have associated DLBCL with inflammation but the GRNs involved in this mechanism
have not yet been explored. The objectives of this current study are to reconstruct
inflammation-associated networks and to understand the effects of inflammation on
the pathogenesis and progression of DLBCL in different clinical stages. | en_US |
dc.language.iso | en | en_US |
dc.publisher | University of the Western Cape | en_US |
dc.subject | Bioinformatics | en_US |
dc.subject | Gene regulatory networks | en_US |
dc.subject | B-cell lymphoma | en_US |
dc.subject | Genes | en_US |
dc.title | Reconstruction of gene regulatory networks of inflammation-associated genes in different clinical stages of diffuse large B-cell lymphoma | en_US |
dc.rights.holder | University of the Western Cape | en_US |